Duchenne muscular dystrophy (DMD) is a severe neuromuscular disease arising from loss-of-function mutations in the dystrophin gene and characterized by progressive muscle degeneration, respiratory insufficiency, cardiac failure, and premature death by the age of thirty.Albeit DMD is one of the most common types of fatal genetic diseases, there is n

One approach to treating cancer and other infections is Photodynamic Therapy (PDT).Numerous treatment modalities including PDT have long recognized the need to improve the performance cubs foam finger of nanoscale therapeutic frameworks.Photosensitizers (Ps) are NPs used in PDT, selectively targeting malignant tissues for therapeutic effects, while

Human papillomavirus type 16 (HPV16) E7 is a viral oncoprotein believed to play a major role in cervical cancer.In this study, an antagonist peptide against HPV16E7 protein was first identified from screening the c7c phage display peptide library.The binding specificity and affinity of the selected peptide to HPV16E7 were tested by competitive enzy

RNAi targeting the electron transport chain has been proven to prolong life span in many different species, and experiments specifically with Drosophila melanogaster and Caenorhabditis elegans have shown a distinct role for neurons.To determine which subset of neurons is implicated in this life span extension, we used the GAL4/UAS system to activat